We hereby announce that there has been a change in our company’s management structure.
As of March 31, 2025, Mr. Iku Sugioka has stepped down from his position as CEO, and Mr. Masahiko Kato has resigned from his position as Director. We are pleased to announce that Mr. Yasushi Matsuoka has been appointed as the new CEO effective April 1, 2025.
We would like to inform you of the development of the regenerative medicine cell product “AE101” (indication: bullous keratopathy) in the Chinese region (mainland China, Hong Kong, Macau, and Taiwan) and South Korea as follows:
ActualEyes Inc. announces the implementation of Series C financing by a domestic pharmaceutical company, bringing its accumulated fundraising to 850 million JPY. The Series C round is ongoing and expected to reach 1 billion JPY upon completion.
We are pleased to inform you that the first patient in our domestic Phase II clinical trial of AE101, a regenerative medicine cell product under development by ActualEyes Inc., has successfully received the transplantation. AE101 is designed for the treatment of bullous keratopathy (see Note 1). We are also pleased to report that the necessary safety evaluations have been completed, allowing for the continuation of the trial with subsequent patients.
We are honored to welcome the world-renowned ophthalmologist, Dr. Prema Padmanabhan, as an advisor to our company. Dr. Padmanabhan has been a leading figure in treating corneal diseases at Sankara Nethralaya, one of India’s premier eye hospitals, for many years. Sankara Nethralaya is one of the largest eye specialty hospitals globally, known for its cutting-edge treatments and research, attracting patients and specialists from across India and around the world.
Leveraging Dr. Padmanabhan’s extensive experience and exceptional expertise, our company aims to accelerate the development of treatments for corneal diseases. This collaboration will enable us to swiftly bring innovative therapies to market, significantly improving patients’ quality of life. With Dr. Padmanabhan’s invaluable guidance, we are poised to take our product development to new heights and achieve groundbreaking advancements in the field.
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